Radiopharmaceutical treatment involves administering a radioactive chemical called a radiopharmaceutical to a patient in order to target cancer or other diseased cells. Because the radiopharmaceutical selectively irradiates and destroys cancer cells while limiting radiation exposure to healthy tissue, this treatment is known as “targeted” radionuclide therapy. A radioactive atom is often paired with a targeting molecule that particularly seeks and binds to, in, or near cancer cells. Some radionuclide can target specific cells without the need of a targeting chemical. Here you can learn about dosimetría radiológica

Because thyroid and thyroid cancer cells naturally digest radioactive iodine, physicians have utilised radioiodine to safely treat hyperthyroidism an overactive thyroid gland and some kinds of thyroid cancer for many years. Because therapy may be adjusted to fit the molecular features of a patient’s individual tumour, targeted radionuclide therapy holds promise for personalised treatment of many forms of cancer. Furthermore, because the radiopharmaceutical is delivered by the circulatory system, it can treat tumours throughout the body, even cancer that has spread to other parts of the body as metastatic illness. Surgery and external-beam radiation therapy can only eradicate tumours at the treatment site and not anywhere else in the body.

The phrase “dosimetry” refers to the science of determining radiation dosage by measurement, computation, or a combination of measurement and calculation. Also, it is technically known as “absorbed dose,” and radiation dosimeter is defined as the quantity of radiation energy deposited in tissue divided by the mass of the tissue. The most significant physical element influencing the response of tumours and the rest of the body to radiation is the absorbed dosage.

What is the importance of radiation dosimeter?

The amount of radiation absorbed impacts the extent to which cancers and normal tissues are damaged by radiation. The higher the radiation dosage absorbed by tumours, the more cells will be destroyed by radiation and the greater the possibility of a cure.

However, the higher the absorbed dosage to normal tissues, the more probable and severe the radiation’s unwanted harmful side effects may be. The capacity of radiopharmaceutical treatment to irradiate and efficiently treat cancers throughout the body is a benefit. Yet, some irradiation of normal organs is unavoidable. As a result, the function of dosimetría radiológica in targeted radionuclide therapy is to precisely estimate the administered amount of radiopharmaceutical that will most successfully treat the patient’s ailment while avoiding absorbed levels that damage normal tissues for each patient.